Moderate Interaction Be cautious with this combination:
- Aluminum interacts with VITAMIN D: Aluminum is found in most antacids. Vitamin D can increase how much aluminum the body absorbs. This interaction might be a problem for people with kidney disease. Take vitamin D two hours before, or four hours after antacids.
- Calcipotriene (Dovonex) interacts with VITAMIN D: Calcipotriene is a drug that is similar to vitamin D. Taking vitamin D along with calcipotriene (Dovonex) might increase the effects and side effects of calcipotriene (Dovonex). Avoid taking vitamin D supplements if you are taking calcipotriene (Dovonex).
- Digoxin (Lanoxin) interacts with VITAMIN D: Vitamin D helps your body absorb calcium. Calcium can affect the heart. Digoxin (Lanoxin) is used to help your heart beat stronger. Taking vitamin D along with digoxin (Lanoxin) might increase the effects of digoxin (Lanoxin) and lead to an irregular heartbeat. If you are taking digoxin (Lanoxin), talk to your doctor before taking vitamin D supplements.
- Diltiazem (Cardizem, Dilacor, Tiazac) interacts with VITAMIN D: Vitamin D helps your body absorb calcium. Calcium can affect your heart. Diltiazem (Cardizem, Dilacor, Tiazac) can also affect your heart. Taking large amounts of vitamin D along with diltiazem (Cardizem, Dilacor, Tiazac) might decrease the effectiveness of diltiazem.
- Verapamil (Calan, Covera, Isoptin, Verelan) interacts with VITAMIN D: Vitamin D helps your body absorb calcium. Calcium can affect the heart. Verapamil (Calan, Covera, Isoptin, Verelan) can also affect the heart. Do not take large amounts of vitamin D if you are taking verapamil (Calan, Covera, Isoptin, Verelan).
- Water pills (Thiazide diuretics) interacts with VITAMIN D: Vitamin D helps your body absorb calcium. Some “water pills” increase the amount of calcium in the body. Taking large amounts of vitamin D along with some “water pills” might cause to be too much calcium in the body. This could cause serious side effects including kidney problems.
- Some of these “water pills” include chlorothiazide (Diuril), hydrochlorothiazide (HydroDIURIL, Esidrix), indapamide (Lozol), metolazone (Zaroxolyn), and chlorthalidone (Hygroton).
Minor Interaction Be watchful with this combination:
- Cimetidine (Tagamet) interacts with VITAMIN D: The body changes vitamin D into a form that it can use. Cimetidine might decrease how well the body changes vitamin D. This might decrease how well vitamin D works. But this interaction probably isn’t important for most people.
- Heparin interacts with VITAMIN D: Heparin slows blood clotting and can increase the risk of breaking a bone when used for a long period of time. People taking these medications should eat a diet rich in calcium and vitamin D.
- Low molecular weight heparins (LMWHS) interacts with VITAMIN D: Some medications called low molecular weight heparins can increase the risk of breaking a bone when used for a long periods of time. People taking these medications should eat a diet rich in calcium and vitamin D.
- These drugs include enoxaparin (Lovenox), dalteparin (Fragmin), and tinzaparin (Innohep).
References
Source: WebMD, “Vitamin D”, www.webmd.com/vitamins-supplements/