Limonene

• Limonene is a chemical found in the peels of citrus fruits and in other plants. It is used to make medicine.

• Uses
• Benefits
• Interactions
• Other Names
• References

Uses

• Limonene is used to promote weight loss, prevent cancer, treat cancer, and treat bronchitis.
• In foods, beverages, and chewing gum, limonene is used as a flavoring.
• In pharmaceuticals, limonene is added to help medicinal ointments and creams penetrate the skin.
• In manufacturing, limonene is used as a fragrance, cleaner (solvent), and as an ingredient in water-free hand cleansers.

Benefits

• Limonene may block cancer-forming chemicals and kill cancer cells in the laboratory. But more research is needed to know if this occurs in humans.

Interactions

Moderate Interaction Be cautious with this combination

• Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with LIMONENE: Limonene might increase how quickly the liver breaks down some medications. Taking limonene along with some medications that are changed by the liver can lead to a variety of effects and side effects. Before taking limonene talk to your healthcare provider if you take any medications that are changed by the liver.
  • Some of these medications that are changed by the liver include diclofenac (Cataflam, Voltaren), ibuprofen (Motrin), meloxicam (Mobic), and piroxicam (Feldene), amitriptyline (Elavil), warfarin (Coumadin), glipizide (Glucotrol), losartan (Cozaar), and others.
• Medications that decrease the break down of other medications by the liver (Cytochrome P450 2C19 (CYP2C19) inhibitors) interacts with LIMONENE: Limonene might be broken down by the liver. Taking limonene along with medications that decrease the break down of limonene in the liver might increase the effects and side effects of limonene.
  • Some medications that might decrease the breakdown of limonene in the liver include cimetidine (Tagamet), fluvoxamine (Luvox), omeprazole (Prilosec); ticlopidine (Ticlid), topiramate (Topamax), and others.
• Medications that decrease the break down of other medications by the liver (Cytochrome P450 2C9 (CYP2C9) inhibitors) interacts with LIMONENE: Limonene might be broken down by the liver. Taking limonene along with medications that decrease the break down of limonene in the liver might increase the effects and side effects of limonene.
  • Some medications that might decrease the breakdown of limonene in the liver include amiodarone (Cordarone), fluconazole (Diflucan), lovastatin (Mevacor), paroxetine (Paxil), zafirlukast (Accolate), and many others.
• Medications that increase the break down of other medications by the liver (Cytochrome P450 2C19 (CYP2C19) inducers) interacts with LIMONENE: Limonene might be broken down by the liver. Taking limonene along with medications that increase the break down of limonene in the liver might decrease the effects of limonene.
  • Some medications that might increase the breakdown of limonene in the liver include carbamazepine (Tegretol), prednisone (Deltasone), and rifampin (Rifadin, Rimactane).
• Medications that increase the break down of other medications by the liver (Cytochrome P450 2C9 (CYP2C9) inducers) interacts with LIMONENE: Limonene might be broken down by the liver. Taking limonene along with medications that increase the break down of limonene in the liver might decrease the effects of limonene.
  • Some medications that might increase the breakdown of limonene in the liver include rifampin (Rifadin, Rimactane) and secobarbital (Seconal).

Other Names

Alpha-Limonene, Alpha-Limonène, Dipentene, D-Limonene, D-Limonène, L-Limonene, L-Limonène, Limonène, Limoneno, R-Limonene, R-Limonène, S-Limonene, S-Limonène.

References

Source: WebMD, “Limonene”, www.webmd.com/vitamins-supplements/