Moderate Interaction Be cautious with this combination:
- Cyclosporine (Neoral, Sandimmune) interacts with PEPPERMINT: The body breaks down cyclosporine (Neoral, Sandimmune) to get rid of it. Peppermint Oil might decrease how quickly the body breaks down cyclosporine (Neoral, Sandimmune). Taking Peppermint Oil products along with cyclosporine (Neoral, Sandimmune) might increase the risk of side effects for cyclosporine (Neoral, Sandimmune).
- Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with PEPPERMINT: Peppermint oil and leaf might decrease how quickly the liver breaks down some medications. Taking peppermint oil along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking peppermint oil, talk to your healthcare provider if you take any medications that are changed by the liver
- Some medications that are changed by the liver include amitriptyline (Elavil), haloperidol (Haldol), ondansetron (Zofran), propranolol (Inderal), theophylline (Theo-Dur, others), verapamil (Calan, Isoptin, others), and others.
- Medications changed by the liver (Cytochrome P450 2C19 (CYP2C19) substrates) interacts with PEPPERMINT: Peppermint Oil might decrease how quickly the liver breaks down some medications. Taking peppermint oil along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking peppermint oil, talk to your healthcare provider if you take any medications that are changed by the liver
- Some medications that are changed by the liver include omeprazole (Prilosec), lansoprazole (Prevacid), and pantoprazole (Protonix); diazepam (Valium); carisoprodol (Soma); nelfinavir (Viracept); and others.
- Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with PEPPERMINT: Peppermint Oil might decrease how quickly the liver breaks down some medications. Taking peppermint oil along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking peppermint oil, talk to your healthcare provider if you take any medications that are changed by the liver.
- Some medications that are changed by the liver include diclofenac (Cataflam, Voltaren), ibuprofen (Motrin), meloxicam (Mobic), and piroxicam (Feldene); celecoxib (Celebrex); amitriptyline (Elavil); warfarin (Coumadin); glipizide (Glucotrol); losartan (Cozaar); and others.
- Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with PEPPERMINT: Peppermint Oil might decrease how quickly the liver breaks down some medications. Taking peppermint oil along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Before taking peppermint oil, talk to your healthcare provider if you are taking any medications that are changed by the liver
- Some medications changed by the liver include lovastatin (Mevacor), ketoconazole (Nizoral), itraconazole (Sporanox), fexofenadine (Allegra), triazolam (Halcion), and many others.
Minor Interaction Be watchful with this combination:
- Antacids interacts with PEPPERMINT: Some Peppermint Oil products are covered with a special coating. Antacids are used to decrease stomach acid. Low stomach acid can cause the coating of these Peppermint Oil products to dissolve too quickly. When peppermint oil products dissolve too quickly they can sometimes cause heartburn and nausea. Take antacids at least two hours after coated Peppermint Oil products.
- Some antacids include calcium carbonate (Tums, others), dihydroxyaluminum sodium carbonate (Rolaids, others), magaldrate (Riopan), magnesium sulfate (Bilagog), aluminum hydroxide (Amphojel), and others.
- Medications that decrease stomach acid (H2-Blockers) interacts with PEPPERMINT: Some Peppermint Oil products are covered with a special coating. Some medications that decrease stomach acid might cause the coating of these peppermint oil products to dissolve too quickly. When peppermint oil products dissolve too quickly they can sometimes cause heartburn and nausea. Take medications that decrease stomach acid at least two hours after coated peppermint oil products
- Some medications that decrease stomach acid include cimetidine (Tagamet), ranitidine (Zantac), nizatidine (Axid), and famotidine (Pepcid).
- Medications that decrease stomach acid (Proton pump inhibitors) interacts with PEPPERMINT: Some Peppermint Oil products are covered with a special coating. Some medications that decrease stomach acid might cause the coating of these peppermint oil products to dissolve too quickly. When peppermint oil products dissolve too quickly they can sometimes cause heartburn and nausea. Take medications that decrease stomach acid at least two hours after coated peppermint oil products
- Some medications that decrease stomach acid include omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex), pantoprazole (Protonix), and esomeprazole (Nexium).
References
Source: WebMD, “Peppermint”, www.webmd.com/vitamins-supplements/