Resveratrol is a member of a group of plant compounds called polyphenols. These compounds are thought to have antioxidant properties, protecting the body against the kind of damage linked to increased risk for conditions such as cancer and heart disease. Resveratrol is found in the skin of red grapes, but other sources include peanuts and berries. Resveratrol has gained a lot of attention for its reported antiaging and disease-combating benefits. Early research, mostly done in test tubes and in animals, suggests that resveratrol might help protect the body against a number of diseases.
- Heart disease: Resveratrol helps reduce inflammation, prevents the oxidation of LDL “bad” cholesterol, and makes it more difficult for platelets to stick together and form the clots that can lead to a heart attack.
- Cancer: Resveratrol is thought to limit the spread of cancer cells and trigger the process of cancer cell death (apoptosis).
- Alzheimer’s disease: Resveratrol may protect nerve cells from damage and the buildup of plaque that can lead to Alzheimer’s.
- Diabetes: Resveratrol helps prevent insulin resistance, a condition in which the body becomes less sensitive to the effects of the blood sugar-lowering hormone, insulin. Insulin resistance is a precursor to diabetes.
- Rodent studies suggest that resveratrol might even help against some of the effects of an unhealthy lifestyle and lead to increased longevity. Resveratrol-treated mice fed a high-calorie diet lived longer than similarly fed mice not given resveratrol. Resveratrol protected mice fed a high-calorie diet from obesity-related health problems by mimicking the effects of caloric restriction.
- Resveratrol has also been linked to prevention of age-related problems such as heart disease and insulin resistance. Researchers believe that resveratrol activates the SIRT1 gene, a biological mechanism that seems to protect the body against the harmful effects of obesity and the diseases of aging.
Because there have been very few studies conducted on humans, doctors still can’t confirm any benefits, and they don’t know what effects these supplements might have on people over the long term. So far, studies have not discovered any severe side effects, even when resveratrol is taken in large doses. However, resveratrol supplements might interact with blood thinners such as warfarin (Coumadin), and nonsteroidal anti-inflammatory medications such as aspirin and ibuprofen, increasing the risk for bleeding.
Source: WebMD, www.webmd.com/heart-disease/resveratrol-supplements