Aralia quinquefolia (Panax quinquefolis) is a herb that grows mainly in North America. Aralia quinquefolia is in such high demand that it has been declared a threatened or endangered species in some states in the United States.
- People take American ginseng by mouth for stress, to boost the immune system, and as a stimulant.
- American ginseng is often used to fight infections such as colds and flu. There is some evidence that it might help prevent colds and flu and make symptoms milder when infections do occur.
- American ginseng is used for other infections including HIV/AIDS, infections of the intestine (dysentery), and particular infections (Pseudomonas infections) that are common in people with cystic fibrosis.
- Some people use American ginseng to improve digestion and for loss of appetite, as well as for vomiting, inflammation of the colon (colitis), and inflammation of the lining of the stomach (gastritis).
- American ginseng is also used for low iron in the blood (anemia), diabetes, insulin resistance related to HIV treatments, cancer-related fatigue, high blood pressure,trouble sleeping (insomnia), nerve pain, erectile dysfunction (ED), fever, hangover symptoms, attention deficit-hyperactivity disorder (ADHD), blood and bleeding disorders, breast cancer, dizziness, headaches, convulsions, fibromyalgia, “hardening of the arteries” (atherosclerosis), memory loss, rheumatoid arthritis, schizophrenia, improving athletic performance, improving mental performance, as an anti-aging aid, menopausal symptoms, complications during pregnancy or childbirth, and for nervous exhaustion (neurasthenia).
- You may also see American ginseng listed as an ingredient in some soft drinks. Oils and extracts made from American ginseng are used in soaps and cosmetics.
Pregnancy and breast-feeding: American ginseng is POSSIBLY UNSAFE in pregnancy. One of the chemicals in Panax ginseng, a plant related to American ginseng, has been linked to possible birth defects. Do not take American ginseng if you are pregnant.
There is not enough reliable information about the safety of taking American ginseng if you are breast feeding. Stay on the safe side and avoid use.
Diabetes: American ginseng might lower blood sugar. In people with diabetes who are taking medications to lower blood sugar, adding American ginseng might lower it too much. Monitor your blood sugar closely if you have diabetes and use American ginseng.
Hormone-sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: American ginseng preparations that contain chemicals called ginsenosides might act like estrogen. If you have any condition that might be made worse by exposure to estrogen, don’t use American ginseng that contains ginsenosides. However, some American ginseng extracts have had the ginsenosides removed (Cold-fX, Afexa Life Sciences, Canada). American ginseng extracts such as these that contain no ginsenosides or contain only a low concentration of ginsenosides do not appear to act like estrogen.
Trouble sleeping (insomnia): High doses of American ginseng have been linked with insomnia. If you have trouble sleeping, use American ginseng with caution.
Schizophrenia (a mental disorder): High doses of American ginseng have been linked with sleep problems and agitation in people with schizophrenia . Be careful when using American ginseng if you have schizophrenia.
Surgery: American ginseng might affect blood sugar levels and might interfere with blood sugar control during and after surgery. Stop taking American ginseng at least 2 weeks before a scheduled surgery.
Warfarin (Coumadin) interacts with Aralia quinquefolia
Warfarin (Coumadin) is used to slow blood clotting. American ginseng has been reported to decrease the effectiveness of warfarin (Coumadin). Decreasing the effectiveness of warfarin (Coumadin) might increase the risk of clotting. It is unclear why this interaction might occur. To avoid this interaction do not take American ginseng if you take warfarin (Coumadin).
Medications for depression (MAOIs) interacts with Aralia quinquefolia
American ginseng might stimulate the body. Some medications used for depression can also stimulate the body. Taking American ginseng along with these medications used for depression might cause side effects such as anxiousness, headache, restlessness, and insomnia.
Some of these medications used for depression include phenelzine (Nardil), tranylcypromine (Parnate), and others.
Medications for diabetes (Antidiabetes drugs) interacts with Aralia quinquefolia
American ginseng might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking American ginseng along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.
Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
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