Blue No. 2 commonly called indigotine, is a synthetic food dye. It was originally discovered in sea snails excrement. Blue 2 lake is the salt of Blue 2.
- It is used in baked goods, cereals, ice cream, snacks, candies and cherries.
In September 2007, a study reported by D. McCann and colleagues in the journal “The Lancet” linked artificial colorings, including Blue No. 2, to hyperactivity. Nearly 300 children in the study were given a beverage with artificial colors and a preservative. Drinking the beverage resulted in increased hyperactivity in the children, which the researchers attributed to the artificial coloring or the preservative or both. As a result, one candy company, Nestlé-Rowntree, stopped selling one of its candies with a blue shell until it replaced the artificial color with a new blue color made from spirulina, a blue-green algae.
In a group of studies reviewed by the Center for Science in the Public Interest, Blue No. 2 did not affect reproduction or cause birth defects in rabbits or rats. However, male rats in one group that received a high dosage of Blue No. 2 had statistically significant increases in brain cancers and other abnormal cell development. No human studies have been reported, and experts disagree about the safety of Blue No. 2, according to the CSPI. However, the U.S. Food and Drug Administration says that FD&C blue no. 2 is safe for use in food and supplements, according to the Code of Federal Regulations. The CSPI asserts that Blue No. 2 is not safe for human consumption. Since it adds nothing to the nutritive value of food and evidence for its safety is questionable, CSPI recommends it not be used in foods.
Source: Whatisthatingredient, http://whatisthatingredient.com/ingredient.php?id=34