Cetrimonium chloride, or cetyltrimethylammonium chloride (CTAC), is a topical antiseptic and surfactant.
The AFH library classifies this ingredient, and all other cationic surfactants, as irritating, allergenic, toxic and lethal if orally ingested. However, it provides very little evidence to support these claims. The Cosmetic Ingredient Review (CIR) Expert Panel also observed evidence of dermal irritation with this ingredient. However, repeated patch tests of concentrations up to .25% did not demonstrate sensitization or allergic reaction, save for some minor irritation during induction. Furthermore, dermal exposure to 2% cetrimonium chloride produced no evidence of toxicity. As a result, the CIR Expert Panel has assessed this ingredient as safe to use in cosmetics at concentrations up to .25%. The EU Cosmetics Directive allows it to be used at a maximum concentrations of .1%.
- None are recorded.
A quaternary ammonium salt or QUAT, cetyltrimethylammonium chloride
Source: TruthinAging, https://www.truthinaging.com/ingredients/centrimonium-chloride