- Gamma linolenic acid is a fatty substance found in various plant seed oils such as borage oil and evening primrose oil. People use it as medicine.
- Gamma linolenic acid (GLA) is used for conditions that affect the skin including systemic sclerosis, psoriasis, and eczema. It is also used for rheumatoid arthritis (RA), polyps in the mouth, high cholesterol and other blood fats, heart disease, metabolic syndrome (Syndrome-X), diabetic nerve pain, attention deficit-hyperactivity disorder (ADHD), depression, depression after childbirth, chronic fatigue syndrome (CFS), and hay fever (allergic rhinitis). Some people use it to prevent cancer and to help breast cancer patients respond faster to treatment with the drug tamoxifen.
- Gamma linolenic acid is an omega-6 fatty acid, which the body can convert to substances that reduce inflammation and cell growth.
- Gamma linolenic acid is POSSIBLY SAFE for most adults when taken by mouth in amounts of no more than 2.8 grams per day for up to a year. It can cause digestive-tract side effects, such as soft stools, diarrhea, belching, and intestinal gas. It can also make blood take longer to clot.
- Bleeding disorders: Gamma linolenic acid might slow blood clotting. There is some concern that it might increase the risk of bruising and bleeding in people with bleeding disorders.
- Surgery: Since gamma linolenic acid might slow blood clotting, there is concern that it might increase the risk of extra bleeding during and after surgery. Stop taking gamma linolenic acid at least 2 weeks before a scheduled surgery.
Moderate Interaction Be cautious with this combination:
- Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with GAMMA LINOLENIC ACID: Gamma linolenic acid might slow blood clotting. Taking gamma linolenic acid along with medications that also slow clotting might increase the chances of bruising and bleeding.
- Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
- ‘Phenothiazines interacts with GAMMA LINOLENIC ACID: Taking gamma linolenic acid with phenothiazines might increase the risk of having a seizure in some people.
- Some phenothiazines include chlorpromazine (Thorazine), fluphenazine (Prolixin), trifluoperazine (Stelazine), thioridazine (Mellaril), and others.
Acide Gammalinolénique, Acide Gamma-Linolénique, Ácido Gama Linolénico, AGL, Gamolenic Acid, GLA, Gammalinolenic Acid, Gamma-Linolenic Acid, (Z,Z,Z)-Octadeca-6,9,12-trienoic acid.
Source: WebMD, “Gamma-linolenic acid”, www.webmd.com/vitamins-supplements/