Guaifenesin is an expectorant.
Contents
Uses
Guaifenesin is used to treat coughs and congestion caused by the common cold, bronchitis, and other breathing illnesses.
Benefits
Guaifenesin is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. It has been said to aid in the flow of respiratory tract secretions, allowing ciliary movement to carry the loosened secretions upward toward the pharynx. Thus, it may increase the efficiency of the cough reflex and facilitate removal of the secretions.
Guaifenesin has muscle relaxant and anticonvulsant properties and may be acting as an NMDA receptor antagonist.
Caution
This product is usually not used for ongoing cough from smoking or long-term breathing problems (such as chronic bronchitis, emphysema) unless directed by your doctor.
Side-effects of guaifenesin include nausea, vomiting, formation of kidney stones, diarrhea, and constipation. Nausea and vomiting can be reduced by taking guaifenesin with meals. The risk of forming kidney stones during prolonged use can be reduced by maintaining good hydration and increasing the pH of urine. Rarely, severe allergic reactions may occur, including a rash or swelling of the lips or face, which may require urgent medical assistance. Mild dry mouth or chapped lips may also occur when taking this medication. Drinking a glass of water is recommended each time one takes guaifenesin.
Guaifenesin increases the analgesic effect of paracetamol (acetaminophen) and aspirin, increases the sedative effects of alcohol, tranquilisers, sleep-pills and total anesthetics. Guaifenesin increases the effects of medication that decrease muscle tone.
Interactions
None are recorded.
Other names
guaiphenesin, glyceryl guaiacolate
Reference
Source: Wikipedia, https://en.wikipedia.org/wiki/Guaifenesin
WebMD, http://www.webmd.com/drugs/2/drug-3350-118/guaifenesin-oral/guaifenesin-oral/details