Pyridoxine is one form of vitamin B6. Its hydrochloride salt pyridoxine hydrochloride is used as vitamin B6 dietary supplement.
- Pyridoxine is used for preventing and treating low levels of pyridoxine (pyridoxine deficiency) and the “tired blood” (anemia) that may result. It is also used for heart disease; high cholesterol; reducing blood levels of homocysteine, a chemical that might be linked to heart disease; and helping clogged arteries stay open after a balloon procedure to unblock them (angioplasty).
- Women use pyridoxine for premenstrual syndrome (PMS) and other menstruation problems, “morning sickness” (nausea and vomiting) in early pregnancy, stopping milk flow after childbirth, depression related to pregnancy or using birth control pills, and symptoms of menopause.
- Pyridoxine is also used for Alzheimer’s disease, attention deficit-hyperactivity disorder (ADHD), Down syndrome, autism, diabetes and related nerve pain, sickle cell anemia, migraine headaches, asthma, carpal tunnel syndrome, night leg cramps, muscle cramps, arthritis, allergies, acne and various other skin conditions, and infertility. It is also used for dizziness, motion sickness, preventing the eye disease age-related macular degeneration (AMD), seizures, convulsions due to fever, and movement disorders (tardive dyskinesia, hyperkinesis, chorea), as well as for increasing appetite and helping people remember dreams.
- Some people use pyridoxine for boosting the immune system, eye infections, bladder infections, and preventing cancer and kidney stones.
- Pyridoxine is also used to overcome certain harmful side effects related to radiationtreatment and treatment with medications such as mitomycin, procarbazine, cycloserine, fluorouracil, hydrazine, isoniazid, penicillamine, and vincristine.
- Pyridoxine is frequently used in combination with other B vitamins in vitamin B complex products.
Several observations have suggested that low dietary intake of vitamin B6 is associated with higher risk of having heart disease. In addition, vitamin B6 has been shown to play a role in lowering blood levels of homocysteine; high levels of this amino acid appear to be associated with heart disease, but it is not clear whether lowering levels of homocysteine will reduce risk of heart disease.
Studies indicate that an adequate vitamin B6 intake is especially important in the elderly, as this group often suffers from impaired immune function. The amount of vitamin B6 required to improve the immune system has been shown to be higher (2.4 mg/day for men; 1.9 mg/day for women) than the current recommended intake.
Because of mixed study findings, it is presently unclear whether supplementation with vitamin B6 and other B vitamins might lessen age-related cognitive decline (e.g., perception, attention, reaction time, and memory).
Some study findings suggest that increased intake of vitamin B6 might decrease the risk of developing kidney stones, while other trials have not shown such relationship
- Pregnancy and breast-feeding: Pyridoxine is LIKELY SAFE for pregnant women when taken under the supervision of their healthcare provider. It is sometimes used in pregnancy to control morning sickness. High doses are UNSAFE. High doses can cause newborns to have seizures.Pyridoxine is LIKELY SAFE for breast-feeding women when used in amounts not larger than 2 mg per day (the recommended dietary allowance). Avoid using higher amounts. Not enough is known about the safety of pyridoxine at higher doses in breast-feeding women.
- Amiodarone (Cordarone) interacts with PYRIDOXINE (VITAMIN B6)
Amiodarone (Cordarone) might increase your sensitivity to sunlight. Taking vitamin B6 (pyridoxine) along with amiodarone (Cordarone) might increase the chances of sunburn, blistering, or rashes on areas of skin exposed to sunlight. Be sure to wear sunblock and protective clothing when spending time in the sun.
- Phenobarbital (Luminal) interacts with PYRIDOXINE (VITAMIN B6)
The body breaks down phenobarbital (Luminal) to get rid of it. Pyridoxine might increase how quickly the body breaks down phenobarbital (Luminal). This could decrease the effectiveness of phenobarbital (Luminal).
- Phenytoin (Dilantin) interacts with PYRIDOXINE (VITAMIN B6)
The body breaks down phenytoin (Dilantin) to get rid of it. Pyridoxine (vitamin B6) might increase how quickly the body breaks down phenytoin. Taking pyridoxine (vitamin B6) and taking phenytoin (Dilantin) might decrease the effectiveness of phenytoin (Dilantin) and increase the possibility of seizures. Do not take large doses of pyridoxine (vitamin B6) if you are taking phenytoin (Dilantin).
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