Serratia is a genus of Gram-negative, facultatively anaerobic, endosporeforming, rod-shaped bacteria of the Enterobacteriaceae family.



  •  Serrapeptase is used for painful conditions including back pain, osteoarthritis, rheumatoid arthritis, osteoporosis, fibromyalgia, carpel tunnel syndrome, migraine headache, and tension headache.
  • It is also used for conditions that involve pain and swelling (inflammation) including sinusitis, laryngitis, sore throat, ear infections, swelling after surgery, swelling of a vein with the formation of a blood clot (thrombophlebitis), and inflammatory bowel disease (IBD) including ulcerative colitis and Crohn’s disease.
  • Some people use serrapeptase for heart disease and “hardening of the arteries” (atherosclerosis).
  • Women use it for non-cancerous lumpy breasts (fibrocystic breast disease), and nursing mothers use it for breast pain caused by too much milk (breast engorgement).
  • Other uses include treatment of diabetes, leg ulcers, asthma, and pus accumulation (empyema).


  • 1. Atherosclerosis

    Dr. Nieper found that serrapeptase promoted normal blood clotting and reduced the appearance of varicose veins. Other studies found that serrapeptase effectively removes atherosclerotic plaque without hurting any of the healthy cells along the arterial wall.

  • 2. Soothes Redness

    Multiple studies confirm serrapeptase soothes redness and swelling. It promotes a calm, harmonious environment in the body at a cellular level.

  • 3. Helps with Traumatic Injuries

    Serrapeptase is widely used in Europe as a supplement for traumatic injury (such as sprains and torn ligaments), as well as the swelling associated with post-surgical patients.

  • 4. Pain, Edema, and Swelling

    Serrapeptase has been approved as a standard remedy in many European countries for swelling. A double-blind German study on the enzyme found that it could reduce swelling by up to 50% in post-operative patients. Patients taking serrapeptase experienced less pain than the control groups and, by the 10th day of the study, all patients taking the serrapeptase were completely pain-free.

  • 5. Helps with Cystic Breast Disease

    In a double-blind study, serrapeptase was found to reduce breast pain, breast swelling, and induration in 85.7% of the patients taking the supplement. This is related to the fact that the enzyme possesses fibrinolytic, proteolytic and anti-edemic properties.

  • 6. Helps Infections in the Ear, Nose, and Throat

    In one double-blind study, patients with acute or chronic ear, nose or throat diseases found significant symptom regression with serrapeptase. The enzyme can reduce the viscosity of mucous, thus facilitating drainage.

  • 7. Helps with Carpal Tunnel Syndrome

    Recent studies confirm the use of this enzyme for the reduction of symptoms associated with carpal tunnel syndrome.

  • 8. Other Potential Benefits

    Serrapeptase is used for a vast array of applications for human health and disease prevention. This includes therapeutic use for nerve damage, Multiple Sclerosis, chronic ear infections, hay fever, lung congestion, swollen glands, laryngitis, rhinitis, chronic pain, arthritis, back and neck pain, diabetes, ulcers, osteoporosis, prostate problems, rheumatoid arthritis, sports injuries (both prevention and recovery), post-operative scars and lesions, varicose veins, arterial diseases, angina, blood clots, anti-aging, restoration of healthy fibrin metabolism and reduction in C-Reactive Protein.


  • The current research documents a rare side effect of pneumonitis (as noted in “A Case of pneumonitis due to serrapeptase” by Nihon Kyobu Shikkan Gakkai Zasshi in 1989). Other side effects may include allergic reaction, in which case discontinue use and consult a doctor, or minor aches and pains, which should subside in a few weeks of taking serratiopeptidase daily.
  • Possible interactions and dangers of serrapeptase? This enzyme seems to show blood-thinning effects (similar to Aspirin). Taking this supplement while on blood thinners such as warfarin (Coumadin), clopidogrel (Plavix) or ASA (Aspirin) may increase the chances of bleeding or bruising.
  • This increased risk of bleeding may also occur when this enzyme is taken with other natural remedies such as garlic, fish oil and turmeric. Talk to your family doctor first before taking this enzyme if you are taking similar medications or herbal supplements.



Other names

Butterfly Enzyme, Enzyme de Ver de Soie, Extrait de Ver de Soie, SER, Serratia peptidase, Serrapeptidase, Serratiopeptidase, Silk Worm Enzyme, Silkworm Extract


Source: Wikipedia,



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